id: Pfam:PF11768
pfam_id: PF11768
name: WD repeat-containing and planar cell polarity effector protein Fritz
short_name: Frtz
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11768
counters:
  proteins: 1679
  matches: 1831
  proteomes: 1070
  taxa: 3608
  structures: 2
  alphafold_models: 1415
  domain_architectures: 17
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR024511
description: Fritz is a probable effector of the planar cell polarity signaling pathway which regulates
  the septin cytoskeleton in both ciliogenesis and collective cell movements. In Drosophila melanogaster,
  fritz regulates both the location and the number of wing cell prehair initiation sites [[cite:PUB00069294]].