id: Pfam:PF11826
pfam_id: PF11826
name: Vibrionales, replication initiator protein RctB, central region
short_name: RctB_central
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11826
counters:
  proteins: 242
  matches: 242
  proteomes: 216
  taxa: 286
  structures: 2
  alphafold_models: 165
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021781
description: This region is found in the replication initiator protein RctB from Vibrio cholerae ([swissprot:Q9KNG2])
  and similar sequences predominantly found in Vibrionales. RctB mediates oriCII-based replication and
  other regulatory processes. This protein is organised into four domains and adopts a dimeric configuration.
  This entry represents the two central domains, one consisting of a seven-stranded beta- sheet that forms
  the interface of the dimer by forming a swapped configuration with the same domain of the other monomer.
  It seems to be involved in DNA binding [[cite:PUB00091164]].