id: Pfam:PF11870
pfam_id: PF11870
name: Lactate utilisation protein B, C-terminal
short_name: LutB_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11870
counters:
  proteins: 5783
  matches: 5783
  proteomes: 5267
  taxa: 7254
  structures: 0
  alphafold_models: 3480
  domain_architectures: 9
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR024569
description: This domain is functionally uncharacterised. This domain is found at the C-terminal of a
  family of 4Fe-4S, iron-sulphur cluster binding proteins, including Lactate utilisation protein B (LutB).
  These proteins have a perfect 4Fe-4S binding motif C-x(2)-C-x(2)-C-x(3)-CP followed by either a perfect
  or imperfect (the first Cys replaced by Ser) second copy. Members probably bind two 4Fe-4S iron-sulphur
  clusters. This domain is found in LutB proteins in association with the LUD domain ([pfam:PF02589])
  and usually Fer4_8 ([pfam:PF13183]). The LutABC operon is involved in lactate-utilisation and is essential
  [[cite:PUB00076952],[cite:PUB00053899]].