id: Pfam:PF11904
pfam_id: PF11904
name: ANKRD13 C-terminal
short_name: ANKRD13_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11904
counters:
  proteins: 8651
  matches: 9113
  proteomes: 1827
  taxa: 5655
  structures: 0
  alphafold_models: 7470
  domain_architectures: 117
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR055285
description: This domain, and the associated ANK family repeat [pfam:PF00023] domain, are found in ANKRD13
  of which at least 4 subtypes are known to exist, termed A-D. ANKRD13C act as a chaperone for biogenesis
  and folding of the DP receptor for prostaglandin D2 [[cite:PUB00057233]]. ANKRD13A/B/D are ubiquitin-binding
  proteins that specifically recognise and bind Lys-63-linked ubiquitin. They positively regulate the
  internalisation of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell
  membrane [[cite:PUB00155297]].