id: Pfam:PF11931
pfam_id: PF11931
name: SF3a60/Prp9 C-terminal
short_name: SF3a60_Prp9_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11931
counters:
  proteins: 4089
  matches: 4116
  proteomes: 3337
  taxa: 8787
  structures: 52
  alphafold_models: 3491
  domain_architectures: 99
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR024598
description: 'This domain corresponds to the C-terminal region of SF3a60 subunit (Prp9 in yeast counterpart)
  from the highly conserved heterotrimeric complex SF3a found in eukaryotes. It is essential for pre-mRNA
  splicing that functions in spliceosome assembly within the mature U2 snRNP (small ribonucleoprotein
  particle). This domain has two conserved sequence motifs: PIP and CEICG. It contains a zinc-finger domain
  of the C2H2-type which might be important for RNA binding and protein-protein interactions with components
  of the SF3b complex [[cite:PUB00059480]].'