id: Pfam:PF11952
pfam_id: PF11952
name: XRN-Two Binding Domain, XTBD
short_name: XTBD
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11952
counters:
  proteins: 2436
  matches: 2439
  proteomes: 1174
  taxa: 3853
  structures: 1
  alphafold_models: 2113
  domain_architectures: 58
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021859
description: XTBD is a family of eukaryotic proteins that act as an XRN2-binding module. XRN2 is an essential
  exoribonuclease in eukaryotes that processes and degrades a number of different substrates. XTBD is
  found on a number of different proteins to link them to XRN, such as PAXT-1 [[cite:PUB00075685]].