id: Pfam:PF11979
pfam_id: PF11979
name: Smad anchor for receptor activation-like, C-terminal
short_name: SARA_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11979
counters:
  proteins: 3470
  matches: 3678
  proteomes: 1225
  taxa: 3946
  structures: 1
  alphafold_models: 1641
  domain_architectures: 42
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR022557
description: This domain is found at the C-terminal end of a group of animal zinc finger FYVE domain-containing
  proteins, including Smad anchor for receptor activation (SARA), which plays a significant role in TGF-mediated
  signalling. This domain is involved in the interaction with the TGF-beta receptor [[cite:PUB00042868],[cite:PUB00024191]].
  This domain is found associated with [pfam:PF01363].