id: Pfam:PF11998
pfam_id: PF11998
name: Low psii accumulation1 / Rep27
short_name: DUF3493
seed_status: KNOWN_HISTORICAL_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF11998
counters:
  proteins: 1512
  matches: 1514
  proteomes: 698
  taxa: 1944
  structures: 0
  alphafold_models: 1181
  domain_architectures: 38
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021883
description: This family includes members such as low psii accumulation1 (lpa1) from plants as well as
  Rep27 proteins found in unicellular green alga Chlamydomonas reinhardtii. The Arabidopsis LPA1 is a
  chaperone required for efficient photosystem II (PSII) assembly. It binds to psbA during de novo biogenesis
  of PSII [[cite:PUB00086019]]. Other studies show that REP27 in Chlamydomonas reinhardtii chloroplast
  thylakoids, plays a dual role in the regulation of D1 protein turnover by facilitating cotranslational
  biosynthesis insertion (C-terminal domain) and activation (tetratricopeptide repeat [TPR] motifs) of
  the nascent D1 during the PSII repair process [[cite:PUB00138194]].