id: Pfam:PF12004
pfam_id: PF12004
name: Disabled homolog 2-interacting protein, C-terminal domain
short_name: DAB2P_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12004
counters:
  proteins: 7363
  matches: 8025
  proteomes: 1032
  taxa: 3408
  structures: 1
  alphafold_models: 4817
  domain_architectures: 60
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021887
description: This domain is found at the C terminus of some GTPase-activating proteins (also known as
  GAP) found in animals, including Disabled homolog 2-interacting protein (DAB2P). This region is found
  associated with [pfam:PF00616] and [pfam:PF00168], and includes a coiled-coil domain that forms a parallel
  trimer in solution with one helical strand from each monomer [[cite:PUB00100693]].