id: Pfam:PF12013
pfam_id: PF12013
name: Orsellinic acid/F9775 biosynthesis cluster protein D
short_name: OrsD
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12013
counters:
  proteins: 2099
  matches: 2142
  proteomes: 608
  taxa: 1505
  structures: 0
  alphafold_models: 1473
  domain_architectures: 58
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR022698
description: This family of proteins is functionally uncharacterised. This protein is found in eukaryotes.
  Proteins in this family are typically between 247 to 1018 amino acids in length. Family members include
  orsellinic acid/F9775 biosynthesis cluster protein D (orsD) from Emericella nidulans. The orsD gene
  is part of the cluster that encodes components for the biosynthesis of orsellinic acid, as well as biosynthesis
  of the cathepsin K inhibitors F9775 A and F9775 B [[cite:PUB00083127]] [[cite:PUB00083128]], but the
  function of orsD is unknown. OrsD contains two segments that are likely to be C2H2 zinc binding domains.