id: Pfam:PF12037
pfam_id: PF12037
name: ATPase family AAA domain-containing protein 3, N-terminal
short_name: ATAD3_N
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12037
counters:
  proteins: 3619
  matches: 3759
  proteomes: 1805
  taxa: 5566
  structures: 0
  alphafold_models: 3101
  domain_architectures: 69
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR021911
description: This is the conserved N-terminal domain of ATPase family AAA domain-containing protein 3
  (ATAD3) which is involved in dimerisation [[cite:PUB00097486]] and interacts with the inner surface
  of the outer mitochondrial membrane [[cite:PUB00089261]]. This domain is found associated with the AAA
  ATPase domain ([pfam:PF00004]). ATAD3 is essential for mitochondrial network organisation, mitochondrial
  metabolism and cell growth at organism and cellular level. It may also play an important role in mitochondrial
  protein synthesis.