id: Pfam:PF12532
pfam_id: PF12532
name: LmuB C-terminal
short_name: LmuB_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12532
counters:
  proteins: 806
  matches: 806
  proteomes: 765
  taxa: 1702
  structures: 7
  alphafold_models: 478
  domain_architectures: 4
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR022205
description: This entry, previously known as DUF3732 represents the C-terminal region of Salmonella enterica
  Lamassu LmuB. Lamassu is a diverse family of defense systems that protect bacteria, including seventh-pandemic
  strains of Vibrio cholerae, against both plasmids and phage infection. During phage infection, Lamassu
  targets essential cellular processes, thereby halting phage propagation by terminating the infected
  host. This region forms extensive interactions with the LmuB N-terminal region [[cite:PUB00164006]].