id: Pfam:PF12603
pfam_id: PF12603
name: RNA-directed RNA polymerase L, PA-C-like domain
short_name: L_PA-C-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12603
counters:
  proteins: 432
  matches: 432
  proteomes: 131
  taxa: 363
  structures: 13
  alphafold_models: 123
  domain_architectures: 6
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR022531
description: This domain is found in RNA-directed RNA polymerase L from from Bunyavirales. It has been
  described as the PA-C-like domain which forms a narrow and positively charged cleft with the thumb domain,
  where the 3' RNA is likely bound [[cite:PUB00101134]]. It is found in association with [pfam:PF04196].