id: Pfam:PF12941
pfam_id: PF12941
name: HCV NS5a protein C-terminal region
short_name: HCV_NS5a_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12941
counters:
  proteins: 2466
  matches: 2488
  proteomes: 13
  taxa: 165
  structures: 1
  alphafold_models: 25
  domain_architectures: 27
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR024350
description: This is a family of proteins found in the hepatitis C virus. This family contains the C-terminal
  region of the NS5A protein. CC The molecular function of the non-structural 5a protein is uncertain.
  The NS5a protein is phosphorylated when expressed in mammalian cells. It is thought to interact with
  the ds RNA dependent (interferon inducible) kinase PKR, [swissprot:P19525].