id: Pfam:PF12955
pfam_id: PF12955
name: Vacuolar sorting protein Vps3844, C-terminal domain
short_name: Vps3844_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12955
counters:
  proteins: 1295
  matches: 1295
  proteomes: 1272
  taxa: 2694
  structures: 0
  alphafold_models: 1087
  domain_architectures: 19
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR024382
description: This entry represents the C-terminal domain (previously known as DUF3844) of the uncharacterised
  endoplasmic reticulum membrane protein C1709.03 which was renamed to vacuolar sorting protein Vps3844
  [[cite:PUB00156045]]. This domain contains eight largely conserved cysteine residues and the region
  comprising amino acids 354 to 380 is important for protein trafficking to the vacuole. This protein
  is conserved in fungi, particularly S. pombe, but lacks representation in S. cerevisiae [[cite:PUB00156045]].