id: Pfam:PF12993
pfam_id: PF12993
name: Domain of unknown function, E. rectale Gene description (DUF3877)
short_name: DUF3877
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF12993
counters:
  proteins: 140
  matches: 141
  proteomes: 134
  taxa: 223
  structures: 0
  alphafold_models: 81
  domain_architectures: 4
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR024539
description: Based on Eubacterium rectale gene EUBREC_0237. As seen in gene expression experiments (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE14737),
  it appears to be upregulated in the presence of Bacteroides thetaiotaomicron vs when isolated in culture
  [[cite:PUB00056060]].