id: Pfam:PF13157
pfam_id: PF13157
name: Endospore appendages
short_name: Enas
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13157
counters:
  proteins: 398
  matches: 398
  proteomes: 183
  taxa: 298
  structures: 4
  alphafold_models: 244
  domain_architectures: 7
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR025055
description: The surface of Bacillus and Clostridium endospores is decorated with long filamentous endospores
  appendages that resemble pili from Gram- negative and Gram-positive bacteria. They show two morphologies,
  the main or Staggered-type (S-Ena) which accounts for 90% of the fibres, and the Ladder-like (L-Ena)
  which is smaller and less abundant. They are a novel class of Gram-positive pili, consisting in single
  domain subunits with a jellyroll topology comprised by two juxtaposed beta-sheets. This domain represents
  the S-Ena core. Disulfide bonding through the N-terminal connector peptide that precedes this domain
  stabilizes longitudinally the fibres, bridging the helical turns. This results in flexible pili, highly
  resistant to environmental harsh such as heat, drought, and chemical damage [[cite:PUB00098173]].