id: Pfam:PF13186
pfam_id: PF13186
name: Iron-sulfur cluster-binding domain
short_name: SPASM
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13186
counters:
  proteins: 16680
  matches: 16683
  proteomes: 9267
  taxa: 14353
  structures: 10
  alphafold_models: 11292
  domain_architectures: 93
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR023885
description: This domain occurs as an additional C-terminal iron-sulfur cluster binding domain in many
  radical SAM domain, [pfam:PF04055] proteins. The domain occurs in a number of proteins that modify a
  protein to become an active enzyme, or a peptide to become a ribosomal natural product. The domain is
  named SPASM because it occurs in the maturases of Subilitosin, PQQ, Anaerobic Sulfatases, and Mycofactocin.