id: Pfam:PF13320
pfam_id: PF13320
name: Glycoside hydrolase 123, catalytic domain
short_name: GH123_cat
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13320
counters:
  proteins: 2146
  matches: 2177
  proteomes: 1422
  taxa: 2901
  structures: 19
  alphafold_models: 1398
  domain_architectures: 151
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR025150
description: This domain is found at the C terminus of protein members of the glycoside hydrolase family
  123, including N-acetylgalactosaminidase from Clostridium perfringens. This enzyme removes specific
  terminal N-D-acetylgalactosamine from glycosphingolipids. This catalytic domain adopts an alpha/beta
  barrel configuration with a two-stranded beta sheet and a pair of alpha-helices at the C-terminal end
  [[cite:PUB00100654],[cite:PUB00151590]].