id: Pfam:PF13491
pfam_id: PF13491
name: 4TM region of DNA translocase FtsK/SpoIIIE
short_name: FtsK_4TM
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13491
counters:
  proteins: 13056
  matches: 13056
  proteomes: 12945
  taxa: 18378
  structures: 0
  alphafold_models: 8415
  domain_architectures: 15
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR025199
description: 4TM_FtsK is the integral membrane domain of the FtsK DNA tranlocases. During sporulation
  in Bacillus subtilis, the SpoIIIE protein is believed to form a translocation pore at the leading edge
  of the nearly closed septum. The E. coli FtsK protein is homologous to SpoIIIE, and can free chromosomes
  trapped in vegetative septa.