id: Pfam:PF13652
pfam_id: PF13652
name: Putative quorum-sensing-regulated virulence factor
short_name: QSregVF
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13652
counters:
  proteins: 432
  matches: 432
  proteomes: 430
  taxa: 489
  structures: 1
  alphafold_models: 240
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR025203
description: This is a family of short ~14 kDa proteins from Psuedomonas. The structure of UniProtKB:Q9HY15
  a secreted protein has been solved and deposited as PDB:3npd. It comprises one structural domain with
  five beta-strands and five alpha-helices. Various comparative structural prediction methods plus its
  genomic location point to the protein forming a functional dimer with its adjacent genomic partner,
  UniProtKB:Q9HY14, in [pfam:PF12843]. Together these might be regulated by the other product from the
  PotABCD operon, namely the putrescine-binding periplasmic protein UniProtKB:Q9HY16. which has been implicated
  in quorum-sensing. QSregVF is certainly up-regulated in quorum-sensing, and is predicted to be a virulence
  factor [[cite:PUB00075641]].