id: Pfam:PF13665
pfam_id: PF13665
name: Toxin PAAR-like domain
short_name: Tox-PAAR-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13665
counters:
  proteins: 1800
  matches: 1800
  proteomes: 1029
  taxa: 1707
  structures: 1
  alphafold_models: 1061
  domain_architectures: 93
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
description: This domain is found at the N-terminal of bacterial toxin systems, including Tse7 (type IV
  secretion exported 7) from Pseudomonas aeruginosa, a type VI secretion exported toxin with DNase activity
  that induces growth arrest and ultimately DNA degradation within target cell [[cite:PUB00098743]]. The
  structure of this domain has a PAAR-like organisation necessary for interaction with T6SS VgrG tip and
  correct toxin delivery [[cite:PUB00098743],[cite:PUB00098744]].