id: Pfam:PF13826
pfam_id: PF13826
name: Monooxygenase af470-like
short_name: Monooxy_af470-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13826
counters:
  proteins: 2841
  matches: 2846
  proteomes: 2518
  taxa: 4153
  structures: 0
  alphafold_models: 1872
  domain_architectures: 20
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR025444
description: This entry includes Monooxygenase af470-like from Aspergillus fumigatus, which is part of
  the fma gene cluster that mediates the biosynthesis of fumagillin, a meroterpenoid with numerous biological
  activities [[cite:PUB00081410]]. It has been suggested that af470 mediates the oxidative cleavage of
  the terminal alkene of the dodecapentaenoate side chain into the carboxylic acid present in fumagillin
  [[cite:PUB00081411]].