id: Pfam:PF13886
pfam_id: PF13886
name: TM7S3/TM198-like domain
short_name: TM7S3_TM198
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13886
counters:
  proteins: 6044
  matches: 6101
  proteomes: 2578
  taxa: 6899
  structures: 0
  alphafold_models: 5110
  domain_architectures: 80
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR025256
description: This domain is found at the C-terminal end of human Transmembrane 7 superfamily member 3
  (TM7SF3), which is is involved in the inhibition of cytokine-induced death of pancreatic beta cells,
  towards the N terminus of human Transmembrane protein 198 (TM198), which plays a role in Wnt signalling
  and in similar proteins mainly found in animal, fungi and bacteria. This domain is predicted to adopt
  an all alpha-helical structure.