id: Pfam:PF13907
pfam_id: PF13907
name: Chromodomain-helicase-DNA-binding protein 1-like, C-terminal
short_name: CHD1-like_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13907
counters:
  proteins: 6052
  matches: 6053
  proteomes: 2985
  taxa: 7935
  structures: 8
  alphafold_models: 905
  domain_architectures: 106
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR025260
description: This domain is found at the C-terminus of chromodomain-helicase-DNA-binding proteins, including
  Chromodomain-helicase-DNA-binding protein 1 from humans (CHD1), an ATP-dependent chromatin-remodeling
  factor which acts as substrate recognition component of the transcription regulatory histone acetylation
  (HAT) complex SAGA. This helical domain consists of five alpha-helices organised in a variant helical
  bundle topology. Its surface is positively charged and can bind dsDNA and nucleosomes, but its specific
  function remains unknown [[cite:PUB00100856],[cite:PUB00100857],[cite:PUB00091268]].