id: Pfam:PF13959
pfam_id: PF13959
name: ATP-dependent rRNA helicase SPB4-like, C-terminal extension
short_name: CTE_SPB4
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13959
counters:
  proteins: 15982
  matches: 15992
  proteomes: 3488
  taxa: 9181
  structures: 50
  alphafold_models: 13653
  domain_architectures: 216
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR025313
description: 'This short domain is found at the C-terminus of many helicase proteins, including ATP-dependent
  rRNA helicase SPB4 from Saccharomyces cerevisiae, which is involved in the biogenesis of 60S ribosomal
  subunits. SPB4 is organised into four domains: dual RecA domains ([pfam:PF00270] and [pfam:PF00271]),
  a C-terminal extension (CTE, represented by this entry) and a C-terminal tail ([pfam:PF23681]). This
  domain packs closely onto the catalytic core and engages the four nucleotides immediately 5'' to those
  within the RNA binding pocket. It shows a mainly alpha- helical structure [[cite:PUB00153742]].'