id: Pfam:PF14027
pfam_id: PF14027
name: Questin oxidase-like
short_name: Questin_oxidase
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF14027
counters:
  proteins: 4856
  matches: 4969
  proteomes: 2173
  taxa: 4131
  structures: 7
  alphafold_models: 3719
  domain_architectures: 72
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR025337
description: This family consists of oxidoreductases involved in the synthesis of different polyketides
  and derivatives. Questin oxidase GedK from Aspergillus terreus catalyzes the ring cleavage of the anthraquinone
  questin to form benzophenone desmethylsulochrin [[cite:PUB00086982]]. It is part of the gene cluster
  that mediates the biosynthesis of geodin, an intermediate in the biosynthesis of other natural products
  [[cite:PUB00081405]]. MdpL from Emericella nidulans is part of the gene cluster that mediates the biosynthesis
  of monodictyphenone [[cite:PUB00086983]].