id: Pfam:PF14203
pfam_id: PF14203
name: Putative transposon-transfer assisting protein
short_name: TTRAP
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF14203
counters:
  proteins: 567
  matches: 567
  proteomes: 270
  taxa: 505
  structures: 1
  alphafold_models: 353
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR025468
description: TTRAP is a family of small bacterial proteins largely from Clostrium difficile. From comparative
  and other structural studies of the PDB:2L7K, UniProtKB:Q18AW3, it has been suggested that this family
  is required for interacting with other proteins in order to facilitate the transfer of the transposon
  CTn4 between different bacterial species. PDB:2L7K comprises an alpha-helical fold of four alpha-helices
  leading to the production of two clefts, the larger of which displays two highly conserved residues
  in close proximity, Glu-8 and Lys-48. The gene concerned is part of an operon within transposon CTn4,
  and is expressed alongside a putative DNA primase, a DNA topoisomerase and conjugal transfer proteins
  [[cite:PUB00075684]].