id: Pfam:PF14793
pfam_id: PF14793
name: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases
short_name: DUF4478
seed_status: KNOWN_HISTORICAL_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF14793
counters:
  proteins: 2624
  matches: 2624
  proteomes: 2618
  taxa: 3448
  structures: 9
  alphafold_models: 1594
  domain_architectures: 5
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR027820
description: This is an N-terminal domain found in pyrimidine/purine nucleotide 5'-monophosphate nucleosidases
  (PpnN) in bacteria. PpnN catalyzes the hydrolysis of the N-glycosidic bond of diverse pyrimidine and
  purine nucleotide 5'-monophosphates, to form ribose 5-phosphate and the corresponding free base. It
  can use AMP, GMP, IMP, CMP, dTMP and UMP as substrates [[cite:PUB00084997]]. It is found in association
  with [pfam:PF03641] and [pfam:PF11892].