id: Pfam:PF14926
pfam_id: PF14926
name: Cilia- and flagella-associated protein 300
short_name: CFAP300
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF14926
counters:
  proteins: 1441
  matches: 1484
  proteomes: 1112
  taxa: 3546
  structures: 0
  alphafold_models: 1279
  domain_architectures: 26
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR029416
description: CFAP300 is a cilia- and flagella-associated protein that is essential for assembly of dynein
  arms. Mutations in the CFAP300 gene (C11orf70) cause defective cilia motility and primary ciliary dyskinesia
  [[cite:PUB00089790],[cite:PUB00089791]].