id: Pfam:PF14983
pfam_id: PF14983
name: Sperm-associated microtubule inner protein 10
short_name: SPMIP10-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF14983
counters:
  proteins: 332
  matches: 333
  proteomes: 297
  taxa: 1153
  structures: 7
  alphafold_models: 289
  domain_architectures: 5
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR027965
description: This family (previously DUF4513) represents homologs of Sperm-associated microtubule inner
  protein 10 (SPMIP10). SPMIP10 is a microtubule inner protein (MIP) part of the axonemal dynein-decorated
  doublet microtubules (DMTs). It plays a role in the stabilisation of the interacting protomers of TEKTL1
  - a tektin-like molecule that forms a filament in the cleft between protofilaments A11 and A12 . In
  the EM structure of sperm DMTs, SPMIP10 cradles the inter-TEKTL1 interface while interacting with protofilaments
  A11 and A12 [[cite:PUB00151496]].