id: Pfam:PF15021
pfam_id: PF15021
name: Shieldin complex subunit 1, C-terminal domain
short_name: SHLD1_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF15021
counters:
  proteins: 368
  matches: 368
  proteomes: 284
  taxa: 964
  structures: 0
  alphafold_models: 327
  domain_architectures: 3
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR053898
description: SHLD1, also known as RINN3, is a component of the shieldin complex, a vertebrate-specific
  protein complex which functions as a downstream effector in the 53BP1 pathway, regulates NHEJ (non-homologous
  end joining) [[cite:PUB00089626],[cite:PUB00154232]]. This entry represents a conserved helical domain
  found at the C-terminal of SHLD1.