id: Pfam:PF15027
pfam_id: PF15027
name: MGT5A-like, N-terminal
short_name: MGT5A_N
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF15027
counters:
  proteins: 1799
  matches: 1810
  proteomes: 816
  taxa: 2563
  structures: 4
  alphafold_models: 1642
  domain_architectures: 13
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR027833
description: This domain is found at the N-terminal end of human Alpha-1,6 -mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
  A (MGT5A) [[cite:PUB00155403]] and similar sequences mainly found in vertebrates. MGT5A is a glycosyltransferase
  family 18 enzyme that also has the catalytic region [pfam:PF15024]. This domain, which shows an all
  helical structure, plays a critical role in the recognition of glycoprotein substrates [[cite:PUB00155403],[cite:PUB00155404],[cite:PUB00155405]].
  It is also found in Coiled -coil domain-containing protein 126, a smaller sequence that only contains
  this domain.