id: Pfam:PF15077
pfam_id: PF15077
name: Membrane-anchored junction protein
short_name: MAJIN
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF15077
counters:
  proteins: 583
  matches: 668
  proteomes: 394
  taxa: 1419
  structures: 3
  alphafold_models: 499
  domain_architectures: 11
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR027816
description: Membrane-anchored junction protein (MAJIN) is a meiosis-specific telomere-associated protein
  involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous
  pairing and synapsis. It is a component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap
  exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the
  protective cap of telomeric chromosomes [[cite:PUB00077546]].