id: Pfam:PF15127
pfam_id: PF15127
name: Small membrane A-kinase anchor protein
short_name: SmAKAP
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF15127
counters:
  proteins: 678
  matches: 678
  proteomes: 631
  taxa: 1983
  structures: 1
  alphafold_models: 628
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR027969
description: SmAKAP is a small membrane-bound PKA-RI-specific protein kinase A-anchoring protein, referred
  to as small membrane-AKAP. It is probably tethered to the plasma membrane most through a dual acylation
  of its N-terminal Met-Gly-Cys- motif (myristoylation and palmitoylation, respectively). It specifically
  targets PKA-RI isoforms to the plasma membrane. It localizes to plasma membranes, is enriched at cell-cell
  junctions and associates with filopodia [[cite:PUB00067440]].