id: Pfam:PF15384
pfam_id: PF15384
name: PAXX, PAralog of XRCC4 and XLF, also called C9orf142
short_name: PAXX
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF15384
counters:
  proteins: 757
  matches: 777
  proteomes: 553
  taxa: 1971
  structures: 20
  alphafold_models: 650
  domain_architectures: 7
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR027873
description: PAXX is a set of eukaryotic proteins that belong to the XRCC4 superfamily of DNA-double-strand
  break-repair proteins. PAXX interacts directly with DSB-repair protein Ku and is recruited to DNA-damage
  sites in cells thus functioning with XRCC4 and XLF to bring about DSB repair and cell survival in response
  to DSB-inducing agents [[cite:PUB00074304]].