id: Pfam:PF16062
pfam_id: PF16062
name: ADP-ribosylhydrolase MavL-like
short_name: MavL-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16062
counters:
  proteins: 581
  matches: 750
  proteomes: 319
  taxa: 1126
  structures: 2
  alphafold_models: 470
  domain_architectures: 24
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR032063
description: This entry represents a class of MavL-like macrodomain enzymes whose representative members
  show unique selectivity for mono-ADP-ribosylated arginine residue in synthetic substrates, including
  [swissprot:Q9W2W5] and [swissprot:Q9W4J9] from Drosophila melanogaster, which are distantly related
  to MavL from Legionella pneumophila [[cite:PUB00155313]]. They are (ADP-ribosyl)hydrolases that share
  a mode of ADP-ribose interaction distinct from previously characterised macrodomains [[cite:PUB00155313]].