id: Pfam:PF16088
pfam_id: PF16088
name: BLOC-1-related complex sub-unit 7
short_name: BORCS7
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16088
counters:
  proteins: 1361
  matches: 1365
  proteomes: 1162
  taxa: 3955
  structures: 1
  alphafold_models: 1200
  domain_architectures: 32
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR032143
description: This is a family of unknown function found in eukaryotes. Family members include BORCS7 (BLOC-1-related
  complex sub-unit 7) also known as Diaskedin (from the Ancient Greek 'diaskedazo', meaning 'to disperse')
  or C10orf32. It constitutes sub-unit 7 of the BORC complex (BLOC-one-related complex). BORC is a multisubunit
  complex that regulates the positioning of lysosomes at the cell periphery, and consequently affects
  cell migration. BORC associates with the lysosomal membrane, where it functions to recruit the small
  GTPase Arl8. This initiates a series of interactions that promote the microtubule-guided transport of
  lysosomes toward the cell periphery [[cite:PUB00082308]][[cite:PUB00074975]].