id: Pfam:PF16107
pfam_id: PF16107
name: Domain of unknown function (DUF4825)
short_name: DUF4825
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16107
counters:
  proteins: 643
  matches: 643
  proteomes: 613
  taxa: 1000
  structures: 0
  alphafold_models: 387
  domain_architectures: 16
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR032250
description: This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases,
  where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterised proteins
  in a broad range of bacteria. Its association with BlaR1 homologues suggests it may be involved in substrate-,
  possibly antibiotic-binding, but this prediction has not been verified experimentally.