id: Pfam:PF16162
pfam_id: PF16162
name: Kiwa protein KwaB-like
short_name: KwaB
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16162
counters:
  proteins: 539
  matches: 539
  proteomes: 527
  taxa: 1329
  structures: 4
  alphafold_models: 348
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR032359
description: This family includes Kiwa protein KwaB from E.coli, a component of antiviral defense system
  Kiwa composed of KwaA and KwaB. The expression of Kiwa in E.coli (strain MG1655) confers resistance
  to phages lambda and SECphi18 [[cite:PUB00097806]]. This family also includes a phylogenetically broad
  range of bacteria associated with the human gut microbiome. A member of this family from Lactobacillus
  casei CRL 705 is part of the gene cluster involved in synthesis of bacteriocin toxin [[cite:PUB00016503]].