id: Pfam:PF16335
pfam_id: PF16335
name: Glutaminase A six helical-hairpin domain
short_name: GtaA_6_Hairpin
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16335
counters:
  proteins: 4215
  matches: 5628
  proteomes: 1856
  taxa: 3600
  structures: 0
  alphafold_models: 3216
  domain_architectures: 90
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR032514
description: This entry represents the six helical-hairpin domain found in homologues of Glutaminase A
  from Aspergillus oryzae. Glutaminase catalyzes the hydrolysis of glutamine to glutamic acid and plays
  a key role in nitrogen metabolism. It catalyzes the hydrolysis not only of L-glutamine but also of D-glutamine
  [[cite:PUB00035385]]. This domain share similarity with six-hairpin glycosidases.