id: Pfam:PF17237
pfam_id: PF17237
name: ERMES regulator 1
short_name: Emr1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17237
counters:
  proteins: 622
  matches: 622
  proteomes: 607
  taxa: 1555
  structures: 0
  alphafold_models: 536
  domain_architectures: 10
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR035195
description: The endoplasmic reticulum-mitochondria encounter structure (ERMES) complex creates contact
  sites between the endoplasmic reticulum and mitochondria, playing crucial roles in interorganelle communication,
  mitochondrial fission, mtDNA inheritance, lipid transfer, and autophagy. Emr1, also known as Mco6 in
  budding yeasts, mediates the formation ERMES foci, thereby contributing to the formation of ER-mitochondrial
  contact sites [[cite:PUB00099560]].