id: Pfam:PF17238
pfam_id: PF17238
name: NUP160, helical domain
short_name: NUP160_helical_2
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17238
counters:
  proteins: 611
  matches: 619
  proteomes: 352
  taxa: 989
  structures: 1
  alphafold_models: 101
  domain_architectures: 31
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR035192
description: This entry represents a helical domain that can be found in NUP160, also known as SAR1, a
  nucleoporin protein in Arabidopsis thaliana. It is a member of the NUP107-160 nuclear pore sub-complex
  [[cite:PUB00085245]]. NUP160 plays a role in normal auxin signalling, which works in synergy with ethylene
  to control various ethylene-dependent phenomena [[cite:PUB00155768]]. Also, it contributes to pathogen
  defense [[cite:PUB00085247]], nucleocytoplasmic mRNA export [[cite:PUB00155768]], and is required for
  disease resistance [[cite:PUB00085246]].