id: Pfam:PF17397
pfam_id: PF17397
name: TSX
short_name: TSX
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17397
counters:
  proteins: 371
  matches: 371
  proteomes: 340
  taxa: 1027
  structures: 0
  alphafold_models: 352
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR035352
description: This is a family of unknown function found in Chordata. This domain is located downstream
  the N-terminal of Fip1 [pfam:PF05182]. Family members such as [swissprot:P70537] and [swissprot:P70675]
  contain this domain. The Tsx gene resides at the X-inactivation centre and once thought to encode a
  protein expressed in testis. However, this was disputed upon further analysis. ORF and immunostaining
  analysis concluded that Tsx may be non-coding. Tsx long transcript is abundantly expressed in meiotic
  germ cells, embryonic stem cells, and brain. In vertebrates, Fip1 is the evolutionary precursor of eutherian
  Tsx, hence its location upstream from the Tsx gene [[cite:PUB00085337]].