id: Pfam:PF17664
pfam_id: PF17664
name: Cilia- and flagella-associated protein HOATZ-like
short_name: HOATZ-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17664
counters:
  proteins: 543
  matches: 562
  proteomes: 412
  taxa: 1509
  structures: 0
  alphafold_models: 455
  domain_architectures: 4
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR040681
description: This entry represents cilia- and flagella-associated protein, HOATZ, and related proteins,
  found in metazoa. In mice HOATZ is encoded by the gene designated 4833427G06Rik (C11orf88). Mouse Hoatz
  mRNA is specifically expressed in tissues with motile cilia and flagella [[cite:PUB00135090]]. Hoatz
  knockout mice developed hydrocephalus and male infertility, and the ependymal cilia frequently showed
  disorganised axonemes [[cite:PUB00135090]].