id: Pfam:PF17721
pfam_id: PF17721
name: POU domain class 2-associating factor 2
short_name: POU2AF2
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17721
counters:
  proteins: 608
  matches: 616
  proteomes: 446
  taxa: 1498
  structures: 0
  alphafold_models: 520
  domain_architectures: 8
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR037655
description: POU domain class 2-associating factor 2 (also known as Protein OCA-T1) is a transcriptional
  coactivator that specifically associates with POU2F3 [[cite:PUB00101325]], forming a complex that drives
  the development of tuft cells, a rare chemosensory cells that coordinate immune and neural functions
  within mucosal epithelial tissues [[cite:PUB00101325]].