id: Pfam:PF18127
pfam_id: PF18127
name: Nicotinamide phosphoribosyltransferase, N-terminal domain
short_name: NAMPT_N
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF18127
counters:
  proteins: 3721
  matches: 3729
  proteomes: 2538
  taxa: 5725
  structures: 99
  alphafold_models: 2846
  domain_architectures: 36
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR041529
description: This is the N-terminal domain found in Nicotinamide phosphoribosyltransferase (NAMPT) present
  in Homo sapiens. NAMPT captures nicotinamide (NAM) and replenish the nicotinamide adenine dinucleotide
  (NAD+) pool during ADP-ribosylation and transferase reactions [[cite:PUB00059630]].