id: Pfam:PF18231
pfam_id: PF18231
name: L-serine kinase SerK, C-terminal domain
short_name: SerK_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF18231
counters:
  proteins: 39
  matches: 39
  proteomes: 38
  taxa: 74
  structures: 7
  alphafold_models: 38
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR040867
description: This domain is found in the C-terminal region of free serine kinase (SerK) in the hyperthermophilic
  archaeon Thermococcus kodakarensis. SerK converts ADP and l-serine (Ser) into AMP and O-phospho-l-serine
  (Sep), which is a precursor of l-cysteine. The domain is not conserved in the ParB/Srx family. The differences
  between SerK and the other members of the ParB/Srx family is concentrated in the C-terminal region,
  which may include residues involved in the Sep binding [[cite:PUB00091306]]. Members of this group are
  mainly found in archaea.