id: Pfam:PF18446
pfam_id: PF18446
name: Domain of unknown function (DUF5611)
short_name: DUF5611
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF18446
counters:
  proteins: 400
  matches: 400
  proteomes: 400
  taxa: 674
  structures: 1
  alphafold_models: 374
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR040713
description: This is a domain of unknown function. Studies of the TA0095 gene product indicate that this
  96-residue hypothetical protein from Thermoplasma acidophilum is a member of the COG4004 orthologous
  group of unknown function found in Archaea bacteria. The structure displays an alpha/beta two-layer
  sandwich architecture formed by three alpha-helices and five beta-strands. Furthermore, structural homologs
  indicate that the TA0095 structure belongs to the TBP-like fold [[cite:PUB00047999]].