id: Pfam:PF19336
pfam_id: PF19336
name: Domain of unknown function (DUF5921)
short_name: DUF5921
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF19336
counters:
  proteins: 807
  matches: 808
  proteomes: 656
  taxa: 2039
  structures: 3
  alphafold_models: 720
  domain_architectures: 8
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR045803
description: This family represents a domain of unknown function located between the Transcription factor
  IIIC subunit delta N-term ([pfam:PF12657]) and the Putative zinc-finger of transcription factor IIIC
  complex ([pfam:PF12660]) within the transcription Factor IIIC 90 kDa subunit (TFIIIC-delta/TFIIIC90,
  also known as general transcription factor 3C polypeptide 4). TFIIIC is a multisubunit complex that
  directly recognises promoter elements and recruits TFIIIB and RNA polymerase III, being absolutely required
  for RNA polymerase III transcription. TFIIIC90 has an intrinsic histone acetyltransferase activity with
  a substrate specificity for histone H3 [[cite:PUB00056254]]. This domain is likely to be involved in
  the interaction with other components of the TFIIIC complex.